HIV Mutation Detail Information

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Mutation Information

Mutation Site	Q114L
Mutation Type	Amino acid level
Gene/Protein/Region Type	Env

Literature Information

PubMed PMID	31776278
Disease	HIV infection/AIDS
Published Year	2020
Journal	Journal of virology
Title	Boosting with AIDSVAX B/E Enhances Env Constant Region 1 and 2 Antibody-Dependent Cellular Cytotoxicity Breadth and Potency.
Author	Easterhoff D,Pollara J,Luo K,Tolbert WD,Young B,Mielke D,Jha S,O'Connell RJ,Vasan S,Kim J,Michael NL,Excler JL,Robb ML,Rerks-Ngarm S,Kaewkungwal J,Pitisuttithum P,Nitayaphan S,Sinangil F,Tartaglia J,Phogat S,Kepler TB,Alam SM,Wiehe K,Saunders KO,Montefiori DC,Tomaras GD,Moody MA,Pazgier M,Haynes BF,Ferrari G
Evidence	An A32-specific mutant protein was designed (AE.A244g120Delta11 F53S H72L V75A E106K D107H S110A Q114L) to identify A32-like MAb responses.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation