HIV Mutation Detail Information

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Mutation Information
Mutation Site Q105H
Mutation Type Amino acid level
Gene/Protein/Region Type Env
Viral Reference AF038399.1
Country Montreal and canda
Literature Information
PubMed PMID 32457241
Disease HIV infection/AIDS
Published Year 2020
Journal mBio
Title The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding Site.
Author Prévost J,Tolbert WD,Medjahed H,Sherburn RT,Madani N,Zoubchenok D,Gendron-Lepage G,Gaffney AE,Grenier MC,Kirk S,Vergara N,Han C,Mann BT,Chénine AL,Ahmed A,Chaiken I,Kirchhoff F,Hahn BH,Haim H,Abrams CF,Smith AB 3rd,Sodroski J,Pazgier M,Finzi A
Evidence Introduction of the LM substitutions (H/Q61Y, Q105H, V108I, N474D, I475M, and K476R) restored this interaction.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation