HIV Mutation Detail Information

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Mutation Information

Mutation Site	P90A
Mutation Type	Amino acid level
Gene/Protein/Region Type	CA

Literature Information

PubMed PMID	32545337
Published Year	2020
Journal	Viruses
Title	Daxx Inhibits HIV-1 Reverse Transcription and Uncoating in a SUMO-Dependent Manner.
Author	Maillet S,Fernandez J,Decourcelle M,El Koulali K,Blanchet FP,Arhel NJ,Maarifi G,Nisole S
Evidence	Disruption of CypA-CA interactions by either treatment with cyclosporine or its analogues (e.g., Debio 025) or by mutation within CA (e.g., G89V or P90A) decreased HIV-1 infection, by affecting uncoating or reverse transcription in certain cell types.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation