|
Mutation Information
|
Mutation Site
|
P78A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Nef |
Literature Information
|
PubMed PMID
|
22651890
|
|
Published Year
|
2012 |
|
Journal
|
Retrovirology |
|
Title
|
Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix. |
|
Author
|
Kuo LS,Baugh LL,Denial SJ,Watkins RL,Liu M,Garcia JV,Foster JL |
|
Evidence
|
It was subsequently reported that the single mutations, P72A and P75A, are only partially defective for MHCI downregulation, but the P78A mutation abolishes this activity.
|
|
|
HIV Mutation Detail Information