Mutation Information
Mutation Site
|
P72A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Nef |
Literature Information
PubMed PMID
|
31186327
|
Published Year
|
2019 |
Journal
|
mBio |
Title
|
Potent Enhancement of HIV-1 Replication by Nef in the Absence of SERINC3 and SERINC5. |
Author
|
Wu Y,Olety B,Weiss ER,Popova E,Yamanaka H,Göttlinger H |
Evidence
|
However, in another study, a P69/P72A mutation in Nef had no effect on HIV-1 replication in primary CD4+ cells and only partially impaired CD4 downregulation by Nef.
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