Mutation Information
Mutation Site
|
P69A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Nef |
Literature Information
PubMed PMID
|
22651890
|
Published Year
|
2012 |
Journal
|
Retrovirology |
Title
|
Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix. |
Author
|
Kuo LS,Baugh LL,Denial SJ,Watkins RL,Liu M,Garcia JV,Foster JL |
Evidence
|
On the other hand, the P69A mutation has been shown to render Nef incapable of Nef/activated PAK2 complex formation.
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