HIV Mutation Detail Information

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Mutation Information
Mutation Site P49A
Mutation Type Amino acid level
Gene/Protein/Region Type Vif
Combined Mutation vif.K50A+vif.P49A
Literature Information
PubMed PMID 28302150
Published Year 2017
Journal Retrovirology
Title Identification of a tripartite interaction between the N-terminus of HIV-1 Vif and CBFβ that is critical for Vif function.
Author Desimmie BA,Smith JL,Matsuo H,Hu WS,Pathak VK
Evidence In addition, we included double mutants P49A-K50A and I51-S52A, because of their proximity to other double mutants that showed significant defects in CBFbeta binding.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation