|
Mutation Information
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Mutation Site
|
P422Q |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Gag |
|
Relevant Drug
|
PIs |
Literature Information
|
PubMed PMID
|
25253273
|
|
Disease
|
HIV infection/AIDS
|
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Published Year
|
2014 |
|
Journal
|
Retrovirology |
|
Title
|
HIV-1 Gag C-terminal amino acid substitutions emerging under selective pressure of protease inhibitors in patient populations infected with different HIV-1 subtypes. |
|
Author
|
Li G,Verheyen J,Theys K,Piampongsant S,Van Laethem K,Vandamme AM |
|
Evidence
|
Specifically, patients failing LPV/r-based regimens developed one of the following Gag substitution patterns: L363W + E477Q, F363L + N389T + P422Q + P455L, K411Q, P472S + P474L, K415R + I469T, M138L, A374T or G420A.
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HIV Mutation Detail Information