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HIV Mutation Detail Information

> P421A Search Result


Mutation Information
Mutation Site P421A
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Literature Information
PubMed PMID 31943114
Published Year 2020
Journal Nucleic acids research
Title Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase.
Author Nguyen PDM,Zheng J,Gremminger TJ,Qiu L,Zhang D,Tuske S,Lange MJ,Griffin PR,Arnold E,Chen SJ,Zou X,Heng X,Burke DH
Evidence The singly substituted p51 subunits were co-expressed with wild-type p66 and purified to yield eight enzymatically active mutant RTs (N418A, T419A, P420A, P421A, L422A, V423A, K424A and L425A) (Supplementary Figure S11).
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation