Mutation Information
Mutation Site
|
P373S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Gag |
Literature Information
PubMed PMID
|
31622432
|
Published Year
|
2019 |
Journal
|
PloS one |
Title
|
Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study. |
Author
|
Dicker I,Zhang S,Ray N,Beno BR,Regueiro-Ren A,Joshi S,Cockett M,Krystal M,Lataillade M |
Evidence
|
In the first approach, NL4-3 Gag P373S virus was sequentially passaged beginning at a low concentration of GSK3532795 (either 1x or 2xEC50).
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