HPV Mutation Detail Information

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Mutation Information
Mutation Site P36T
Mutation Type Amino acid level
Gene/Protein/Region Type E4
Amino acid_Mutation C3437A
Genotype/Subtype HPV16
Country Romania
Literature Information
PubMed PMID 25143263
Disease Cervical carcinoma; Squamous-cell carcinoma; Cervical intraepithelial neoplasia
Published Year 2014
Journal Archives of virology
Title Molecular variants of human papilloma virus 16 E2, E4, E5, E6 and E7 genes associated with cervical neoplasia in Romanian patients.
Author Plesa A,Anton G,Iancu IV,Diaconu CC,Huica I,Stanescu AD,Socolov D,Nistor E,Popa E,Stoian M,Botezatu A
Evidence These substitutions result in amino acid changes (T22A, P36T, A43K, Q53R, L62I and L62P, respectively) and seem to be important in malignancy progression.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation