|
Mutation Information
|
Mutation Site
|
P36L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PreS2 |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
M12906
|
|
Relevant Drug
|
hepatitis B immunoglobulin (HBIG) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
19272629
|
|
Clinical information
|
Yes
|
|
Disease
|
HBV infection
|
|
Published Year
|
2009 |
|
Journal
|
Virology |
|
Title
|
Association between genomic heterogeneity of hepatitis B virus and intrauterine infection. |
|
Author
|
Cheng H,Su H,Wang S,Shao Z,Men K,Li M,Li S,Zhang J,Xu J,Zhang H,Yan Y,Xu D |
|
Evidence
|
The clones with mutations such as amino acid P110S in preS1 region, P36L in preS2 region and C107R in S region might infect fetuses more readily.
|
|
|
HBV Mutation Detail Information