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Mutation Information
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Mutation Site
|
P34L |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
P12 |
|
Country
|
Caribbean; France; North America; Africa; Brazil |
Literature Information
|
PubMed PMID
|
27553711
|
|
Disease
|
HTLV-1 associated myelopathy/tropical spastic paraparesis
|
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Published Year
|
2016 |
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Journal
|
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases |
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Title
|
Analyses of HTLV-1 sequences suggest interaction between ORF-I mutations and HAM/TSP outcome. |
|
Author
|
Barreto FK,Khouri R,Rego FFA,Santos LA,Castro-Amarante MF,Bialuk I,Pise-Masison CA,Galvão-Castro B,Gessain A,Jacobson S,Franchini G,Alcantara LC Jr |
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Evidence
|
Our analyses demonstrated that some mutations may be associated with the outcome of HAM/TSP (C39R, L40F, P45L, S69G and R88K) or with proviral load (P34L and F61L).
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HTLV1 Mutation Detail Information