EBV Mutation Detail Information

> P268D Search Result

Mutation Information

Mutation Site	P268D
Mutation Type	Amino acid level
Gene/Protein/Region Type	BILF1

Literature Information

PubMed PMID	30647152
Published Year	2019
Journal	mBio
Title	Distinct Roles of Extracellular Domains in the Epstein-Barr Virus-Encoded BILF1 Receptor for Signaling and Major Histocompatibility Complex Class I Downregulation.
Author	Fares S,Spiess K,Olesen ETB,Zuo J,Jackson S,Kledal TN,Wills MR,Rosenkilde MM
Evidence	However, the C28A, Q89A, L167A, R169A, N172A, C258A, and Y266A mutants showed discordant signaling and MHC class I downregulation functions, where C28A, Q89A, L167A, C258A, and Y266A mutants that retained a wt-like signaling showed impaired MHC class I downregulation (Fig. 4E).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation