|
Mutation Information
|
Mutation Site
|
P25A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
C |
|
Genotype/Subtype
|
D |
Literature Information
|
PubMed PMID
|
28205569
|
|
Published Year
|
2017 |
|
Journal
|
Scientific reports |
|
Title
|
Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms. |
|
Author
|
Zhou Z,Hu T,Zhou X,Wildum S,Garcia-Alcalde F,Xu Z,Wu D,Mao Y,Tian X,Zhou Y,Shen F,Zhang Z,Tang G,Najera I,Yang G,Shen HC,Young JA,Qin N |
|
Evidence
|
In contrast, mutations at positions in close contact with HAP-specific groups (P25A, P25S, or V124F) only reduce susceptibility to HAP_R01, but not to SBA_R01.
|
|
|
HBV Mutation Detail Information