|
Mutation Information
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Mutation Site
|
P225H |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
CRF08_BC |
|
Relevant Drug
|
NNRTIs |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
32381145
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Epidemiology and infection |
|
Title
|
The characteristics of pretreatment HIV-1 drug resistance in western Yunnan, China. |
|
Author
|
Chen M,Zhu Q,Xing H,Chen H,Jin X,Dong L,Dai J,Yang M,Yang C,Jia M,Ma Y |
|
Evidence
|
Among the key DRMs for NNRTIs, Y188C/F/L (0.9%, 3/322), K103N (0.6%, 2/322) and G190A (0.3%, 1/322) conferred high-level resistance, K101E (0.9%, 3/322) and P225H (0.9%, 3/322) conferred intermediate resistance and H221Y (0.9%, 3/322) conferred low-level resistance.
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HIV Mutation Detail Information