|
Mutation Information
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Mutation Site
|
P225H |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NNRTIs |
|
Country
|
UK |
Literature Information
|
PubMed PMID
|
30409215
|
|
Clinical information
|
Yes
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
AIDS research and therapy |
|
Title
|
Characterization of minority HIV-1 drug resistant variants in the United Kingdom following the verification of a deep sequencing-based HIV-1 genotyping and tropism assay. |
|
Author
|
Silver N,Paynter M,McAllister G,Atchley M,Sayir C,Short J,Winner D,Alouani DJ,Sharkey FH,Bergefall K,Templeton K,Carrington D,Quiñones-Mateu ME |
|
Evidence
|
The virus from patient SG28 had mutations associated with resistance to ABC (L74I 97.6% frequency), 3TC (M184V 99.7%), and EFV (K103N 98.8%, P225H 99.5%) and had been exposed to RTV, DRV, ABC, 3TC, and EFV.
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HIV Mutation Detail Information