HIV Mutation Detail Information

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Mutation Information

Mutation Site	P214I
Mutation Type	Amino acid level
Gene/Protein/Region Type	Gp120

Literature Information

PubMed PMID	31126879
Published Year	2019
Journal	Immunity
Title	Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Author	Schoofs T,Barnes CO,Suh-Toma N,Golijanin J,Schommers P,Gruell H,West AP Jr,Bach F,Lee YE,Nogueira L,Georgiev IS,Bailer RT,Czartoski J,Mascola JR,Seaman MS,McElrath MJ,Doria-Rose NA,Klein F,Nussenzweig MC,Bjorkman PJ
Evidence	To explore protein-protein interactions at the SF12-Env interface, we examined mutations in positions 214gp120 (P214I, P214Q), 291gp120 (S291P, S291T), 293gp120 (Q/V293E, Q/V293K, Q/V293R), and 444gp120 (R444T) in the Envs of the BG505 and YU2 pseudoviruses.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation