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Mutation Information
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Mutation Site
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P204A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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LMP1 |
Literature Information
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PubMed PMID
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9733827
|
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Published Year
|
1998 |
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Journal
|
Journal of virology |
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Title
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Role of the TRAF binding site and NF-kappaB activation in Epstein-Barr virus latent membrane protein 1-induced cell gene expression. |
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Author
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Devergne O,Cahir McFarland ED,Mosialos G,Izumi KM,Ware CF,Kieff E |
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Evidence
|
This mutant, LMP1(P204A/Q206A), induced 60% of wild-type LMP1 NF-kappaB activation and had approximately 60% of wild-type LMP1 effect on Fas, ICAM-1, CD40, and LFA-3 induction.
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