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Mutation Information
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Mutation Site
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P171A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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BILF1 |
Literature Information
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PubMed PMID
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30647152
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Published Year
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2019 |
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Journal
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mBio |
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Title
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Distinct Roles of Extracellular Domains in the Epstein-Barr Virus-Encoded BILF1 Receptor for Signaling and Major Histocompatibility Complex Class I Downregulation. |
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Author
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Fares S,Spiess K,Olesen ETB,Zuo J,Jackson S,Kledal TN,Wills MR,Rosenkilde MM |
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Evidence
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In ECL-2a, L167A, R169A, and P171A mutants showed a wt-like surface expression level, whereas two mutants, mutants with N172A and R175A located in a closer proximity to the conserved cysteine (C174), showed lower expression than wt EBV-BILF1 did (Fig. 3B).
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EBV Mutation Detail Information