HBV Mutation Detail Information

> P142L Search Result


Mutation Information
Mutation Site P142L
Mutation Type Amino acid level
Gene/Protein/Region Type S
Combined Mutation s.S143L+s.P142L
Genotype/Subtype E
Viral Reference FN594748
Country Italy
Literature Information
PubMed PMID 29596494
Disease Chronic hepatitis B
Published Year 2018
Journal PloS one
Title High rates of chronic HBV genotype E infection in a group of migrants in Italy from West Africa: Virological characteristics associated with poor immune clearance.
Author Malagnino V,Salpini R,Maffongelli G,Battisti A,Fabeni L,Piermatteo L,Colagrossi L,Fini V,Ricciardi A,Sarrecchia C,Perno CF,Andreoni M,Svicher V,Sarmati L
Evidence RT sequence analysis showed the presence of a number of immune escape mutations: strains from all of the patients had a serine at HBsAg position 140; 3 also had T116N, Y100C, and P142L+S143L substitutions; and 1 had a G112R substitution.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation