Mutation Information
Mutation Site
|
P130T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
C |
Relevant Drug
|
lamivudine (LAM) |
Literature Information
PubMed PMID
|
16928212
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2006 |
Journal
|
Journal of gastroenterology and hepatology |
Title
|
Association of core promoter mutations with viral breakthrough in chronic hepatitis B patients on long-term lamivudine therapy. |
Author
|
Kazim SN,Chauhan R,Das BC,Sarin SK |
Evidence
|
In both HBeAg positive patients, E64D (Fig.3a) was the core protein mutation, along with P130T (Fig.3c) in one and T67S in another.
|
|
|