Mutation Information
Mutation Site
|
P127S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Literature Information
PubMed PMID
|
16928212
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2006 |
Journal
|
Journal of gastroenterology and hepatology |
Title
|
Association of core promoter mutations with viral breakthrough in chronic hepatitis B patients on long-term lamivudine therapy. |
Author
|
Kazim SN,Chauhan R,Das BC,Sarin SK |
Evidence
|
In four of the nine patients in this group, one had S143L (Fig. 1d), the second had P120S and P127S, the third had P127A (Fig. 1c) and the fourth patient had the presence of A128V and M133T surface mutants.
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