Mutation Information
Mutation Site
|
P124A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Gag |
Literature Information
PubMed PMID
|
30327442
|
Published Year
|
2018 |
Journal
|
mBio |
Title
|
Identification of a Structural Element in HIV-1 Gag Required for Virus Particle Assembly and Maturation. |
Author
|
Novikova M,Adams LJ,Fontana J,Gres AT,Balasubramaniam M,Winkler DC,Kudchodkar SB,Soheilian F,Sarafianos SG,Steven AC,Freed EO |
Evidence
|
Moreover, residue Q176 in the P122A mutant assumed a conformation different from that seen with CA WT (Fig. 5C and D), while Q176 adopted the WT conformation in the P124A mutant, despite some flexibility (Fig. 5E).
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