|
Mutation Information
|
Mutation Site
|
P120T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
D |
|
Country
|
Iran |
Literature Information
|
PubMed PMID
|
21671883
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2011 |
|
Journal
|
Current HIV research |
|
Title
|
Detection of hepatitis B virus variants in HBV monoinfected and HBV/HIV coinfected Iranian patients under lamivudine treatment. |
|
Author
|
Aghasadeghi MR,Bahramali G,Sadat SM,Farahani A,Mohraz M,Davar Siadat S,Mostafavi E,Memarnejadian A,Ardestani MS,Vahabpour R,Saraji AA,Delbaz SA |
|
Evidence
|
While sS207N (rtQ215S) co-localized in the fourth trans-membrane domain of HBsAg was only detected in monoinfected patients (P=0.01), several additional mutations (sP105A, sI110S/L, sP120S/T, sP127T/L and sS136Y) located in the major hydrophilic region of HBV envelope (amino acid residues90-160) were detected in HBV/HIV coinfected patients
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HBV Mutation Detail Information