HPV Mutation Detail Information

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Mutation Information

Mutation Site	N92S
Mutation Type	Amino acid level
Gene/Protein/Region Type	E7
Amino acid_Mutation	A846G
Genotype/Subtype	HPV18
Viral Reference	NC_001357.1
Country	China

Literature Information

PubMed PMID	23451059
Disease	Cervical carcinoma
Published Year	2013
Journal	PloS one
Title	Sequence variation analysis of HPV-18 isolates in southwest China.
Author	Shen M,Ding X,Li T,Chen G,Zhou X
Evidence	DNA sequence analysis of the HPV-18 E7 region revealed two variations, both of which occurred only once and in the same specimen: a C to T transition at nt640, which did not result in an AA change (Fig. 1G), and an A to G transition at nt864, leading to a N92S AA substitution (n = 1, 1.79%) (Fig. 1H).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation