HIV Mutation Detail Information

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Mutation Information
Mutation Site N74D
Mutation Type Amino acid level
Gene/Protein/Region Type CA
Literature Information
PubMed PMID 32709741
Published Year 2020
Journal Proceedings of the National Academy of Sciences of the United States of America
Title Absence of cGAS-mediated type I IFN responses in HIV-1-infected T cells.
Author Elsner C,Ponnurangam A,Kazmierski J,Zillinger T,Jansen J,Todt D,Döhner K,Xu S,Ducroux A,Kriedemann N,Malassa A,Larsen PK,Hartmann G,Barchet W,Steinmann E,Kalinke U,Sodeik B,Goffinet C
Evidence Strikingly, HIV-1 (CA N74D) and HIV-1 (CA P90A) failed to trigger a detectable elevation of IFIT1 and MX2 mRNA expression in PM1 T cells (SI Appendix, Fig. S6C).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation