HIV Mutation Detail Information

> N656K Search Result

Mutation Information

Mutation Site	N656K
Mutation Type	Amino acid level
Gene/Protein/Region Type	Env
Viral Reference	AAB50262.1

Literature Information

PubMed PMID	31504041
Published Year	2019
Journal	PloS one
Title	Identification of variant HIV envelope proteins with enhanced affinities for precursors to anti-gp41 broadly neutralizing antibodies.
Author	Zhu H,Mathew E,Connelly SM,Zuber J,Sullivan M,Piepenbrink MS,Kobie JJ,Dumont ME
Evidence	In particular, W631R, I642N, and N656K (Table 6), all provide ~2-fold increases in binding in single point assays (p<0.01) compared to W666R alone and the combination of C605R, W631R, I642N, and W666R provides a higher level of binding than any of the paired mutations (Table 6).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation