HIV Mutation Detail Information

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Mutation Information
Mutation Site N656D
Mutation Type Amino acid level
Gene/Protein/Region Type Gp41
Literature Information
PubMed PMID 27992602
Published Year 2016
Journal PLoS pathogens
Title Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer.
Author Khasnis MD,Halkidis K,Bhardwaj A,Root MJ
Evidence We employed resistance mutation N656D in the C-HR region that reduces 5-Helix binding affinity by more than three orders of magnitude (Fig 1C).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation