HIV Mutation Detail Information

> N637K Search Result

Mutation Information

Mutation Site	N637K
Mutation Type	Amino acid level
Gene/Protein/Region Type	Env
Combined Mutation	env.N637K+env.N636S+env.Q590E;env.E647G+env.N637K+env.K588E;env.E647G+env.H643Q+env.N637K+env.Q577R+env.L544S+env.A517V;env.E662G+env.N637K+gp41.T605N+env.K588N+env.L544S;env.H643Q+env.N637K+env.N636S+env.N624D+env.Q577R+env.L544S;env.K665Q+env.H643Q+env.N637K+env.N636S+env.N611D+env.Q577R
Viral Reference	K03455.1
Relevant Drug	T1249;T2635;T20

Literature Information

PubMed PMID	30696772
Published Year	2019
Journal	The Journal of biological chemistry
Title	HIV-1 anchor inhibitors and membrane fusion inhibitors target distinct but overlapping steps in virus entry.
Author	Eggink D,Bontjer I,de Taeye SW,Langedijk JPM,Berkhout B,Sanders RW
Evidence	Furthermore, the HR1-HR2 double mutant V549A/N637K causes T20 dependence.

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation