Mutation Information
Mutation Site
|
N637A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Env |
Country
|
South Africa |
Literature Information
PubMed PMID
|
29950423
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2018 |
Journal
|
Journal of virology |
Title
|
HIV-1 Subtype C-Infected Children with Exceptional Neutralization Breadth Exhibit Polyclonal Responses Targeting Known Epitopes. |
Author
|
Ditse Z,Muenchhoff M,Adland E,Jooste P,Goulder P,Moore PL,Morris L |
Evidence
|
Three plasma samples, including PID5, showed a minor effect with N611D, and PID6 neutralization was reduced by N637A;both mutations affect PGT151, 35022, and VRC34 neutralization.
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