Mutation Information
Mutation Site
|
N625A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Gp120 |
Country
|
US |
Literature Information
PubMed PMID
|
32156815
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
mBio |
Title
|
Maternal Broadly Neutralizing Antibodies Can Select for Neutralization-Resistant, Infant-Transmitted/Founder HIV Variants. |
Author
|
Martinez DR,Tu JJ,Kumar A,Mangold JF,Mangan RJ,Goswami R,Giorgi EE,Chen J,Mengual M,Douglas AO,Heimsath H,Saunders KO,Nicely NI,Eudailey J,Hernandez G,Morgan-Asiedu PK,Wiehe K,Haynes BF,Moody MA,LaBranche C,Montefiori DC,Gao F,Permar SR |
Evidence
|
Ce1176 N88A and Ce1176 N625A, which are diagnostic of gp120/gp41 interface glycan-targeting bNAbs.
|
|
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