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Mutation Information
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Mutation Site
|
N58S |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
E6 |
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Genotype/Subtype
|
HPV16 |
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Country
|
China |
Literature Information
|
PubMed PMID
|
15297193
|
|
Disease
|
Cervical carcinoma
|
|
Published Year
|
2004 |
|
Journal
|
Gynecologic oncology |
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Title
|
Human papillomavirus type 16 E6, E7, and L1 variants in cervical cancer in Indonesia, Suriname, and The Netherlands. |
|
Author
|
de Boer MA,Peters LA,Aziz MF,Siregar B,Cornain S,Vrede MA,Jordanova ES,Kolkman-Uljee S,Fleuren GJ |
|
Evidence
|
The result of PCR showed that the positive rate of HPV16E6 was 82.86%(29/35); 26 of these 29 PCR fragments were sequenced and analyzed, 15 of them maintained prototype (57.69%), 11 have L83V mutation (34.62%), and 2 have L83V/D63E mutation (7.69%).
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HPV Mutation Detail Information