Mutation Information
Mutation Site
|
N462T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Env |
Viral Reference
|
U71182
|
Country
|
China |
Literature Information
PubMed PMID
|
31178836
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2019 |
Journal
|
Frontiers in microbiology |
Title
|
Characteristics of Envelope Genes in a Chinese Chronically HIV-1 Infected Patient With Broadly Neutralizing Activity. |
Author
|
Zhang D,Zou S,Hu Y,Hou J,Hu X,Ren L,Ma L,He X,Shao Y,Hong K |
Evidence
|
Almost all of Env clones presented a mutation N462T, and combined with N460 produced a PNGS, which may be a potential obstruction to the interaction between VRC01 and Env.
|
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