|
Mutation Information
|
Mutation Site
|
N448S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Gp120 |
Literature Information
|
PubMed PMID
|
31126879
|
|
Published Year
|
2019 |
|
Journal
|
Immunity |
|
Title
|
Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope. |
|
Author
|
Schoofs T,Barnes CO,Suh-Toma N,Golijanin J,Schommers P,Gruell H,West AP Jr,Bach F,Lee YE,Nogueira L,Georgiev IS,Bailer RT,Czartoski J,Mascola JR,Seaman MS,McElrath MJ,Doria-Rose NA,Klein F,Nussenzweig MC,Bjorkman PJ |
|
Evidence
|
Disruption of the PNGS at N448gp120 (N448K, N448S) or N262gp120 (N262S, N262W) abrogated SF5 and SF12 neutralization (Table S6).
|
|
|
HIV Mutation Detail Information