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Mutation Information
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Mutation Site
|
N392A |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Gp120 |
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Immune Escape
|
Y |
Literature Information
|
PubMed PMID
|
32433992
|
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Published Year
|
2020 |
|
Journal
|
Structure (London, England : 1993) |
|
Title
|
Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions. |
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Author
|
Seabright GE,Cottrell CA,van Gils MJ,D'addabbo A,Harvey DJ,Behrens AJ,Allen JD,Watanabe Y,Scaringi N,Polveroni TM,Maker A,Vasiljevic S,de Val N,Sanders RW,Ward AB,Crispin M |
|
Evidence
|
As expected, the N295A and N392A deletions resulted in a substantial decrease in antibody binding (Figure 1D).
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HIV Mutation Detail Information