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Mutation Information
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Mutation Site
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N386Q |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Gp120 |
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Viral Reference
|
K03455.1
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Literature Information
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PubMed PMID
|
24758333
|
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Published Year
|
2014 |
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Journal
|
Retrovirology |
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Title
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Impact of amino acid substitutions in the V2 and C2 regions of human immunodeficiency virus type 1 CRF01_AE envelope glycoprotein gp120 on viral neutralization susceptibility to broadly neutralizing antibodies specific for the CD4 binding site. |
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Author
|
Utachee P,Isarangkura-na-ayuthaya P,Tokunaga K,Ikuta K,Takeda N,Kameoka M |
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Evidence
|
In addition, the mutations, N339Q and N386Q, rather slightly reduced the b12 susceptibility of an AE-Env clone, 98CC2 (Figure 1D).
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HIV Mutation Detail Information