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Mutation Information
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Mutation Site
|
N348I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.N348I+rt.M184V;rt.N348I+rt.M184I;rt.N348I+rt.Y181I+rt.Y181C;rt.N348I+rt.K219E+rt.K219Q;rt.N348I+rt.T215Y+rt.T215F;rt.N348I+rt.L210W;rt.N348I+rt.K70R;rt.N348I+rt.D67N;rt.N348I+rt.M41L |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
NNRTIs;NRTIs |
|
Country
|
UK |
Literature Information
|
PubMed PMID
|
18052601
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2007 |
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Journal
|
PLoS medicine |
|
Title
|
N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance. |
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Author
|
Yap SH,Sheen CW,Fahey J,Zanin M,Tyssen D,Lima VD,Wynhoven B,Kuiper M,Sluis-Cremer N,Harrigan PR,Tachedjian G |
|
Evidence
|
The analysis was performed for N348I and for each of the TAMs: M41L, D67N, K70R, L210W, T215Y/F, and K219Q/E.
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HIV Mutation Detail Information