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Mutation Information
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Mutation Site
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N339A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Gp120 |
Literature Information
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PubMed PMID
|
32433992
|
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Published Year
|
2020 |
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Journal
|
Structure (London, England : 1993) |
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Title
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Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions. |
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Author
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Seabright GE,Cottrell CA,van Gils MJ,D'addabbo A,Harvey DJ,Behrens AJ,Allen JD,Watanabe Y,Scaringi N,Polveroni TM,Maker A,Vasiljevic S,de Val N,Sanders RW,Ward AB,Crispin M |
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Evidence
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Of note, the N448A and N386A knockouts, while not directly contributing to the 2G12 epitope, diminished binding to a similar extent as the N339A secondary binding site deletion.
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HIV Mutation Detail Information