Mutation Information
Mutation Site
|
N29S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
E7 |
Genotype/Subtype
|
HPV16 |
Viral Reference
|
K02718.1
|
Literature Information
PubMed PMID
|
22524831
|
Disease
|
Cervical carcinoma
|
Published Year
|
2012 |
Journal
|
Asian Pacific journal of cancer prevention : APJCP |
Title
|
Whole genome analysis of human papillomavirus type 16 multiple infection in cervical cancer patients. |
Author
|
Chansaenroj J,Theamboonlers A,Junyangdikul P,Swangvaree S,Karalak A,Poovorawan Y |
Evidence
|
In the E6 region, amino acid changes at L83V were related to increased cancer progression. An amino acid variation N29S within the E7 oncoprotein significantly associated with severity of lesion was also discovered.
|
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