|
Mutation Information
|
Mutation Site
|
N285H |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
L1 |
|
Genotype/Subtype
|
HPV16 |
Literature Information
|
PubMed PMID
|
28968823
|
|
Published Year
|
2017 |
|
Journal
|
The Journal of infectious diseases |
|
Title
|
Naturally Occurring Single Amino Acid Substitution in the L1 Major Capsid Protein of Human Papillomavirus Type 16: Alteration of Susceptibility to Antibody-Mediated Neutralization. |
|
Author
|
Ning T,Wolfe A,Nie J,Huang W,Chen XS,Wang Y |
|
Evidence
|
The 50% tissue culture infective doses of the other 8 mutant PsVs (G281W, S282P, N285H, S302L, C428W, K430Q, K430H, and K467R) were 1–3 orders of magnitude lower than those for the reference PsVs (Figure 1).
|
|
|
HPV Mutation Detail Information