Mutation Information
Mutation Site
|
N276Q |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Gp120 |
Country
|
US |
Literature Information
PubMed PMID
|
32156815
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
mBio |
Title
|
Maternal Broadly Neutralizing Antibodies Can Select for Neutralization-Resistant, Infant-Transmitted/Founder HIV Variants. |
Author
|
Martinez DR,Tu JJ,Kumar A,Mangold JF,Mangan RJ,Goswami R,Giorgi EE,Chen J,Mengual M,Douglas AO,Heimsath H,Saunders KO,Nicely NI,Eudailey J,Hernandez G,Morgan-Asiedu PK,Wiehe K,Haynes BF,Moody MA,LaBranche C,Montefiori DC,Gao F,Permar SR |
Evidence
|
To map the specificities of maternal-plasma bNAbs, we tested the following mutant viruses: BJOX2000 N160K, BJOX2000 N332A, TRO.11 N332A, TRO.11 N276Q, TRO.11 N279A, and TRO.11 G458Y.
|
|
|