HIV Mutation Detail Information

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Mutation Information
Mutation Site N265D
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug RT1t49
Literature Information
PubMed PMID 33095511
Published Year 2021
Journal Chembiochem : a European journal of chemical biology
Title Characterization of New DNA Aptamers for Anti-HIV-1 Reverse Transcriptase.
Author Ratanabunyong S,Aeksiri N,Yanaka S,Yagi-Utsumi M,Kato K,Choowongkomon K,Hannongbua S
Evidence This aptamer inhibited the WT HIV‐1 RT DNA polymerase function, however, the point mutations at N255D and N265D positions appeared which conferred resistance to the RT1t49.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation