HIV Mutation Detail Information

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Mutation Information
Mutation Site N254D
Mutation Type Amino acid level
Gene/Protein/Region Type IN
Literature Information
PubMed PMID 19014951
Published Year 2009
Journal Journal of molecular biology
Title Defining the DNA substrate binding sites on HIV-1 integrase.
Author Dolan J,Chen A,Weber IT,Harrison RW,Leis J
Evidence Of the chimeras tested, S39T K42H, Y227I, N254D, K258T R262S showed decreased or no activity with HIV-1 substrates and did not cleave the ASV substrates (data not shown).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation