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Mutation Information
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Mutation Site
|
N231T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
L2 |
|
Amino acid_Mutation
|
A4935C |
|
Genotype/Subtype
|
HPV58 |
Literature Information
|
PubMed PMID
|
28794033
|
|
Published Year
|
2017 |
|
Journal
|
Journal of virology |
|
Title
|
Ancient Evolution and Dispersion of Human Papillomavirus 58 Variants. |
|
Author
|
Chen Z,Ho WCS,Boon SS,Law PTY,Chan MCW,DeSalle R,Burk RD,Chan PKS |
|
Evidence
|
A genome-wide association analysis using mutual information (MI) examination identified three additional amino acid changes within L2 (N231T and M446L) and L1 (L5F); 16 synonymous nucleotide mutations within E1, NCR2, L2, L1, and the LCR; and a 12-bp insertion within the LCR as being strongly associated with the E7 T20I/G63S variant (Table 2).
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HPV Mutation Detail Information