EBV Mutation Detail Information

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Mutation Information

Mutation Site	N211A
Mutation Type	Amino acid level
Gene/Protein/Region Type	BZLF1

Literature Information

PubMed PMID	19144704
Published Year	2009
Journal	Journal of virology
Title	Interaction of Epstein-Barr virus BZLF1 C-terminal tail structure and core zipper is required for DNA replication but not for promoter transactivation.
Author	McDonald CM,Petosa C,Farrell PJ
Evidence	Interestingly, the N211A mutation produced a fivefold reduction in DNA replication, perhaps reflecting the central position of N211 within a hydrogen bond network that stabilizes the interaction between the coiled coil and the C-terminal tail (8).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation