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Mutation Information
|
Mutation Site
|
N174T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PreS2 |
|
Combined Mutation
|
pres2.P155Q+pres2.N174T+pres2.N152S |
|
Genotype/Subtype
|
A |
|
Viral Reference
|
M57663
|
Literature Information
|
PubMed PMID
|
16847965
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2006 |
|
Journal
|
Journal of medical virology |
|
Title
|
Identification of hepatitis B virus subgenotype A3 in rural Gabon. |
|
Author
|
Makuwa M,Souquière S,Telfer P,Apetrei C,Vray M,Bedjabaga I,Mouinga-Ondeme A,Onanga R,Marx PA,Kazanji M,Roques P,Simon F |
|
Evidence
|
The analysis of the pre-S2 domain allowed us to determine two amino acid substitutions (N/152/S and N/174/T) specific to the Central African HBV-A3 subgenotype strains and one amino acid substitution (P/155/Q) unique to these new Gabonese HBV-A3 subgenotype isolates.
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HBV Mutation Detail Information