HIV Mutation Detail Information

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Mutation Information
Mutation Site N160K
Mutation Type Amino acid level
Gene/Protein/Region Type Gp120
Literature Information
PubMed PMID 31126879
Published Year 2019
Journal Immunity
Title Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Author Schoofs T,Barnes CO,Suh-Toma N,Golijanin J,Schommers P,Gruell H,West AP Jr,Bach F,Lee YE,Nogueira L,Georgiev IS,Bailer RT,Czartoski J,Mascola JR,Seaman MS,McElrath MJ,Doria-Rose NA,Klein F,Nussenzweig MC,Bjorkman PJ
Evidence Mutation of the CD4-binding site (D368R/D368Kgp120, A281Tgp120), the V3 glycan patch (N332A/N332Kgp120), and the V2 apex epitope (N160Kgp120), alone or in combination, did not abrogate SF5 or SF12 binding (Figure 2A).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation