Mutation Information
Mutation Site
|
N155H |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
IN |
Genotype/Subtype
|
C |
Country
|
India |
Literature Information
PubMed PMID
|
28149058
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2016 |
Journal
|
Bioinformation |
Title
|
Effect of HIV-1 Subtype C integrase mutations implied using molecular modeling and docking data. |
Author
|
Sachithanandham J,Konda Reddy K,Solomon K,David S,Kumar Singh S,Vadhini Ramalingam V,Alexander Pulimood S,Cherian Abraham O,Rupali P,Sridharan G,Kannangai R |
Evidence
|
The molecular docking scores obtained for various mutation models like 3 individual accessory mutations (L74M, T97A and G163R), major mutation (Q148H, N155H) and also in combination of accessory (L74M, T97A and G163R), accessory and major mutations (L74M, T97A, G163R and Q148H), (L74M, T97A, G163R and N155H) were compared with wild type strain.
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