HPV Mutation Detail Information

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Mutation Information

Mutation Site	N147D
Mutation Type	Amino acid level
Gene/Protein/Region Type	L2
Genotype/Subtype	HPV16
Country	Japan

Literature Information

PubMed PMID	33324377
Disease	Cervical carcinoma
Published Year	2020
Journal	Frontiers in microbiology
Title	High Levels of Within-Host Variations of Human Papillomavirus 16 E1/E2 Genes in Invasive Cervical Cancer.
Author	Hirose Y,Yamaguchi-Naka M,Onuki M,Tenjimbayashi Y,Tasaka N,Satoh T,Tanaka K,Iwata T,Sekizawa A,Matsumoto K,Kukimoto I
Evidence	Of the 10 coding-region variations, nine were non-synonymous or missense substitutions, generating variant forms of viral proteins: E1 Q142K, E1 M207I, E1 L262V, E2 D153Y, E2 R302T, E2 A357T, E7 L65F, L1 E52* (*, nonsense mutation), and L2 N147D.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation